The lips, the front two-thirds of the tongue, the gums, the lining inside the cheeks and lips, the floor (bottom) of the mouth under the tongue, the hard palate (bony top of the mouth), and the small area of gum behind the wisdom teeth are all included in this category.
The pharynx is a 5-inch-long hollow tube that runs from beneath the nose to the oesophagus. The nasopharynx (the upper part of the pharynx, behind the nose), the oropharynx (the middle part of the pharynx, comprising the soft palate [the back of the mouth], the base of the tongue, and the tonsils), and the hypopharynx (the lower section of the pharynx, including the tonsils and the tonsils) (the lower part of the pharynx).
The voice box is a small channel in the neck produced by cartilage immediately below the pharynx. The vocal cords are housed in the voice box. It also features a small patch of tissue called the epiglottis that moves to cover the voice box and keep food out of the airways.
The paranasal sinuses, which surround the nose, are small hollow areas in the head’s bones. Inside the nose, there is a hollow chamber called the nasal cavity.
The main salivary glands are located on the mouth’s floor and near the jawbone. Saliva is produced by the salivary glands. Minor salivary glands can be found all over the mouth and throat mucous membranes.
These are the most significant risk factors for head and neck cancers, particularly oral cavity, hypopharyngeal, and voice box malignancies. People who use both tobacco and alcohol are more likely to get these cancers than people who just use one of the two. Tobacco and alcohol use are the leading causes of squamous cell carcinomas of the mouth and voice box in the head and neck. The usage of paan (betel quid) in the mouth, which is a common practice in Southeast Asia, has been linked to a higher risk of mouth cancer.
HPV type 16 is linked to oropharyngeal malignancies involving the tonsils or the base of the tongue. The incidence of oropharyngeal cancers caused by HPV infection is growing in the United States, whereas the incidence of oropharyngeal cancers caused by other causes is decreasing. Chronic HPV infection is responsible for almost three-quarters of all oropharyngeal malignancies. Although HPV can be found in other head and neck cancers, it appears to be the sole cause of oropharyngeal cancer. The causes for this remain a mystery.
Nasopharyngeal carcinoma is linked to occupational wood dust exposure. Certain occupational exposures, such as asbestos and synthetic fibres, have been linked to voice box cancer, although the magnitude of the risk remains unknown. Construction, metal, textile, ceramic, logging, and food workers may be at a higher risk of voice box cancer. Cancers of the paranasal sinuses and nasal cavity are linked to occupational exposure to wood dust, nickel dust, or formaldehyde.
Exposure to radiation Radiation to the head and neck, whether for noncancerous or cancerous disorders, raises the chance of salivary gland cancer.
Some genetic disorders, such as Fanconi anemia, can increase the risk of developing precancerous lesions and cancers early in life.
A lump in the neck or a sore in the mouth or throat that does not heal and is uncomfortable, a persistent sore throat, difficulty swallowing, and a change or hoarseness in the voice are all possible symptoms of head and neck cancer. Other, less dangerous illnesses can also cause these symptoms. Any of these symptoms should be checked out by a doctor or dentist.
Cancers of the head and neck can cause a variety of symptoms:
Surgery is performed to determine the nature of the tumour. Aside from that, surgery is an option.
This procedure is used to remove cancer from the lymph nodes in the neck.
When cancer surgery necessitates the removal of major tissues, such as those in the jaw, skin, tongue, or pharynx, reconstructive surgery is performed to restore the patient’s appearance and function of the affected area. Tissues from other parts of the body, such as the forearm, thigh, or chest, are used to replace the tissues removed from the head and neck region.
In minimally invasive surgery, doctors use specialised instruments such as an endoscope, lasers, and energy devices that are linked to a surgical microscope and a robot to operate on tumours in the head and neck region. The main goal of minimally invasive surgery is to reduce tissue disruption and pain while performing safe and effective cancer surgery. The most significant advantage of this approach is that there is little or no change in speech, swallowing, or appearance following cancer surgery; this translates to a quicker recovery after treatment.
Radiation therapy Radiation therapy is a type of cancer treatment that uses beams of intense energy to kill cancer cells. Radiation therapy most often uses X-rays, but protons or other types of energy also can be used. The term “radiation therapy” most often refers to external beam radiation therapy.
It acts on the entire body and helps in treating the cancerous growth wherever it is located.
Treatment that employs drugs to inhibit the growth of cancer cells, either by killing them or preventing them from dividing. Depending on the type and stage of the cancer being treated, chemotherapy may be administered orally, by injection or infusion, or through the skin.
It is a distinct type of cancer treatment that is based on tumour biology. It focuses on inhibiting tumour growth and metastasis by targeting the tumour microenvironment or specific proteins. The goal of specific molecular targeting in cancer treatment is to develop a “magic bullet” that kills cancer cells while leaving normal or healthy cells alone.
Not all lumps in the neck point towards head and neck cancers. In most cases, these lumps could be swollen lymph nodes, which are caused due to infection or inflammation. However, if these lumps are persistent and do not go away after the inflammation is cured, you must immediately see your doctor who will be thoroughly examining these lumps before arriving at a conclusive diagnosis.
Different head and neck cancer treatments are associated with different side effects. Radiation therapy may lead to fatigue, weight loss, and pain with swallowing. Chemotherapy, on the other hand, may cause nausea, low blood counts, and changes in taste. A few side effects, like nausea, wear off as soon as the treatment ends. However, other side effects, like fatigue and discomfort with swallowing, take some time to improve.
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